Changelog

Source: NEWS.md

escalation 0.2.0

• Added support for treatment combinations by allowing dose to become a vector of indices rather than a scalar.
• Added BOIN COMB design for treatment combinations.

escalation 0.1.102024-06-27

• Added TITE methods

escalation 0.1.92024-05-22

• Fixed inheritance problems with as_tibble, summary and print dose_selector generics
• Added many tests of dose_selector consistency.

escalation 0.1.82024-02-23

• Made tests faster for CRAN

escalation 0.1.7

• Added ability to import and export PatientSamples
• Split the simulation vignette

escalation 0.1.6

• Implement efficient simulation comparison method of Sweeting et al. in simulate_compare()
• Implement BOIN12 design
• Add MTD / OBD selectors for TPI, mTPI, mTPI2 and BOIN12 for final dose choice at end of a trial

escalation 0.1.52023-05-29

• Add mTPI2 dose-finding method
• Fixed some bugs

escalation 0.1.42020-10-18

• Added Neuenschwander, Branson & Sponer’s method for phase I.
• Added Ji et al.’s TPI & mTI methods for phase I.
• Added Thall & Cook’s EffTox method for phase I/II.
• Added Wages & Tait’s method for phase I/II.

escalation 0.1.32020-05-12

• Mainly small changes to comply with dplyr v1.0.
• simulations and crystallised_dose_paths given summary method
• NOTE squash

escalation 0.1.22020-04-14

• Methods for simulation and calculating dose-paths added.
• A bit more on the general selector interface.
• Everything new has tests, and more tests on old stuff.

escalation 0.1.12020-03-08

• Initial release.
• dfcrm, BOIN, 3+3 models supported.
• several objects included to facilitate stopping at different events.
• class for a fixed escalation plan included, as sometimes used with CRM.